If there is a God of modding, I will gladly sacrifice my first born child and my left testicle, if it means that I can play my game without ever having to worry about CTD when saving. I've already done 7 complete playthroughs of Skyrim (from LE) and I don't have the energy to start another one again. ReSaver, removing most saves, Netimmerse Override Cleaner, cc kill player) but none of them were able to completely solve the issue.

The game has gotten very laggy, with any interaction taking more than 5 seconds, sometimes 1 minute (possibly due to the latest immersive interaction). when I was in Deadman's Drink) but I wasn't able to consistently repeat the results. To make it short, lately, whenever I try to manually save or quicksave, the sound cuts off and the game CTD.